Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 38 Reviews
8.2
Supplement Facts
Serving Size: 3 Vegetarian Capsules
Amount Per Serving
%DV
Magnesium (from 2,000 mg Magtein® magnesium L-threonate)
144 mg
34%

Top Medical Research Studies

7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
Pamidronate therapy reduces bone pain
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.

The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More

Most Useful Reviews

9
Effective for calm
109 people found this helpful
Best Mg I've ever used! This magnesium is great! I'm a naturopath and have tried many types of magnesium. This one genuinely induces a sense of calm, balance and prepares me for sound sleep through the night. Within a few days, I noticed a change. It's been about three weeks now and my neck/muscle pain has disappeared. Very happy with this product. Thank you!
Read More
9
Chronic pain relief
48 people found this helpful
I was having a terrible day with severe pain. I’ve suffered from debilitating headaches and was diagnosed with cluster headaches and occipital neuralgia. I experienced relief after years of chronic pain. Despite trying numerous treatments, this magnesium was what I had been lacking. I would like to thank God for leading me to the remedy my body needed. I hope my review assists someone else in finding what works when others fail.
Read More
7.5
Cognitive improvement
13 people found this helpful
Excellent product, top quality. The magnesium is precisely packaged and is a patented form (Magtein® = Magnesium L-Threonate), which became available in 2010. It can cross the blood-brain barrier, increasing magnesium levels in the brain by up to 15%. This has noticeably improved my cognitive ability, lessened my migraines, reduced muscle pain, and enhanced my sleep quality significantly.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
  • All Researches
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
Pamidronate therapy reduces bone pain
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.

The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More

User Reviews

USERS' SCORE
Good
Based on 38 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective for calm
109 people found this helpful
Best Mg I've ever used! This magnesium is great! I'm a naturopath and have tried many types of magnesium. This one genuinely induces a sense of calm, balance and prepares me for sound sleep through the night. Within a few days, I noticed a change. It's been about three weeks now and my neck/muscle pain has disappeared. Very happy with this product. Thank you!
Read More
9
Chronic pain relief
48 people found this helpful
I was having a terrible day with severe pain. I’ve suffered from debilitating headaches and was diagnosed with cluster headaches and occipital neuralgia. I experienced relief after years of chronic pain. Despite trying numerous treatments, this magnesium was what I had been lacking. I would like to thank God for leading me to the remedy my body needed. I hope my review assists someone else in finding what works when others fail.
Read More
7.5
Cognitive improvement
13 people found this helpful
Excellent product, top quality. The magnesium is precisely packaged and is a patented form (Magtein® = Magnesium L-Threonate), which became available in 2010. It can cross the blood-brain barrier, increasing magnesium levels in the brain by up to 15%. This has noticeably improved my cognitive ability, lessened my migraines, reduced muscle pain, and enhanced my sleep quality significantly.
Read More
9
Improved sleep quality
11 people found this helpful
High-quality, effective magnesium! I buy magnesium for my family, especially for my dad, who struggles with joint and muscle pain and sleep issues. He takes one capsule before bed and has normalised his sleep, falling asleep easily without pain. The effect has been quickly noticeable, and we intend to continue using this form of neuromagnesium.
Read More
10
Bone pain gone
4 people found this helpful
Just awesome! I have felt very comfortable after using it, and my bone pain is gone.
Read More

Frequently Asked Questions

9
Effective for calm
109 people found this helpful
Best Mg I've ever used! This magnesium is great! I'm a naturopath and have tried many types of magnesium. This one genuinely induces a sense of calm, balance and prepares me for sound sleep through the night. Within a few days, I noticed a change. It's been about three weeks now and my neck/muscle pain has disappeared. Very happy with this product. Thank you!
10
Bone pain gone
4 people found this helpful
Just awesome! I have felt very comfortable after using it, and my bone pain is gone.
9
Pregnancy relief
3 people found this helpful
Magnesium Threonate is high quality and highly absorbed, though slightly pricey. Despite this, I find it worth following for discounts. It contains only quality ingredients and is perfect for breastfeeding. It quickly alleviates muscle pain during pregnancy within just fifteen minutes of taking it. Highly recommended after trying various types; consult a doctor for use.
9
Chronic pain relief
48 people found this helpful
I was having a terrible day with severe pain. I’ve suffered from debilitating headaches and was diagnosed with cluster headaches and occipital neuralgia. I experienced relief after years of chronic pain. Despite trying numerous treatments, this magnesium was what I had been lacking. I would like to thank God for leading me to the remedy my body needed. I hope my review assists someone else in finding what works when others fail.
9
Improved sleep quality
11 people found this helpful
High-quality, effective magnesium! I buy magnesium for my family, especially for my dad, who struggles with joint and muscle pain and sleep issues. He takes one capsule before bed and has normalised his sleep, falling asleep easily without pain. The effect has been quickly noticeable, and we intend to continue using this form of neuromagnesium.
7.5
Cognitive improvement
13 people found this helpful
Excellent product, top quality. The magnesium is precisely packaged and is a patented form (Magtein® = Magnesium L-Threonate), which became available in 2010. It can cross the blood-brain barrier, increasing magnesium levels in the brain by up to 15%. This has noticeably improved my cognitive ability, lessened my migraines, reduced muscle pain, and enhanced my sleep quality significantly.
7.5
Bone density boost
1 people found this helpful
Magnesium is essential for bone formation, assisting calcium absorption and activating vitamin D in the kidneys, vital for bone health. Adequate magnesium levels are linked to increased bone density and decreased injury risk, particularly osteoporosis in postmenopausal women.
9
Bone health support
1 people found this helpful
Magnesium positively impacts bone growth, normalises heart rate, lowers blood pressure, and regulates blood sugar levels while eliminating muscle cramps and reducing joint pain. When combined with calcium, it increases bone mineral density. The quality and ingredients are excellent.
10
Convulsions improved
3 people found this helpful
This is salvation! I gave this magnesium to my mother, who experienced tonic convulsions exacerbated by post-COVID complications. Her condition has improved significantly since she began taking it with other medications. I’m thrilled to find a magnesium form that acts quickly and effectively.
7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.

References

  1. Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. doi:10.3389/fbioe.2023.1153969
  2. Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593.
  3. Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.
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